Full List of Publications with TOC
(214) Song, H.; Mikami, T.; Majima, S.; Bode, J. W. external pageAtomic Tailoring of Ubiquitin Side Chains Influences E2-Mediated Ubiquitin Chain Formationcall_made Helv. Chim. Acta 2024, e202400003.
Preprint: external pagehttps://doi.org/10.26434/chemrxiv-2023-26rl0call_made
(213) Gazzi, T.; Heinke, M.; Landolt, F.; Bode, J. W. external pageChemical Synthesis of Secretoglobin 3A2 Covalent Homodimer and Photocaged Monomeric Variantscall_made Angew. Chem. Int. Ed. 2024, e202404992.
(212) Weidner, P.; Saar, D.; Söhn, M.; Schroeder, T.; Yu, Y.; Zöllner, F. G.; Ponelies, N.; Zhou, X.; Zwicky, A.; Rohrbacher, F. N.; Pattabiraman, V. R.; Tanriver, M.; Bauer, A.; Ahmed, H.; Ametamey, S.M.; Riffel, P.; Seger, R.; Bode, J. W.; Wade, R. C.; Ebert, M. P.A.; Kragelund, B. B.; Burgermeister, E. external pageMyotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interactioncall_made Cancer Letters 2024, 588, 216783.
(211) Tanriver M.; Müller M.; Levavsseur M. D.; Richards D.; Majima S.; deMello A.; Yamauchi Y.; Bode, J. W. external pagePeptide-Directed Attachment of Hydroxylamines to Specific Lysines of IgG Antibodies for Bioconjugations with Acylboronatescall_made Angew. Chem. Int. Ed. 2024, Early View.
Preprint: external pagehttps://doi.org/10.26434/chemrxiv-2023-4f6krcall_made
(210) Götz, J.; Jackl, M. K.; Jindakun, C.; Marziale, A. N.; André, J.; Gosling, D. J.; Springer, C.; Palmieri, M.; Reck, M.; Luneau, A.; Brocklehurst, C. E.; Bode, J. W. external pageHigh-Throughput Synthesis Provides Data for Predicting Molecular Properties and Reaction Successcall_made. Sci. Adv. 2023, 9, eadj2314.
(209) Mikami T.; Majima S.; Song H.; Bode, J. W. external pageBiocompatible Lysine Protecting Groups for the Chemoenzymatic Synthesis of K48/K63 Heterotypic and Branched Ubiquitin Chains.call_made ACS Cent. Sci. 2023, ASAP Article.
Preprint: external pagehttps://doi.org/10.26434/chemrxiv-2023-hlk3fcall_made
(208) Farnung, J.; Muhar, M.; Liang, J. R.; Tolmachova, K. A.; Benoit, R. M.; Corn, J. E.; Bode, J. W. external pageSemisynthetic LC3 Probes for Autophagy Pathways Reveal a Noncanonical LC3 Interacting Region Motif Crucial for the Enzymatic Activity of Human ATG3.call_made ACS Cent. Sci. 2023, 9, 1025-1034.
Preprint: external pagehttps://doi.org/10.1101/2022.08.02.502437call_made
(207) Coin, G.; Jiang T.; Bordi, S.; Nichols, P. L.; Bode, J. W.; Wanner, B. external pageAutomated, Capsule-Based Suzuki–Miyaura Cross Couplings.call_madeexternal pagecall_made Org. Lett. 2023, ASAP Article.
(206) Beyer, D.; Vaccarin, C.; Deupi, X.; Mapanao, A. K.; Cohrs, S.; Sozzi-Guo, F.; Grundler, P. V.; van der Meulen, N. P.; Wang, J.; Tanriver, M.; Bode, J. W.; Schibli, R.; Müller, C. external pageA tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides.call_made EJNMMI Research 2023, 13, 32.
(205) Neumann, K.; Vujinovic, A.; Kamara, S.; Baldauf, S.; Bode, J. W. external pageSynthesis of Multi-Module Low Density Lipoprotein Receptor Class A Domains with Acid Labile Cyanopyridiniumylides (CyPY) as Aspartic Acid Masking Groupscall_made, RSC Chem. Biol. 2023, 4, 292-299.
-Preprint: external pagehttps://doi.org/10.26434/chemrxiv.14482983.v1call_made
(204) Farnung, J.; Tolmachova, K. A.; Bode, J. W. external pageInstallation of electrophiles onto the C-terminus of recombinant ubiquitin and ubiquitin-like proteinscall_made Chem. Sci. 2023, 14, 121-129.
(203) MacMillan, A. E.; Wu, W. W. X.; Nichols, P. L.; Wanner, B. M.; Bode, J. W. external pageA Vending Machine for Drug-like Molecules – Automated Synthesis of Virtual Screening Hitscall_made Chem. Sci. 2022, 13, 14292-14299.
-Preprint: external pagehttps://doi.org/10.26434/chemrxiv-2022-htpw2call_made
(202) Scott, T. A.; Verest, M.; Farnung, J.; Forneris, C. C.; Robinson, S. L.; Ji, X.; Hubrich, F.; Chepkirui, C.; Richter, D. U.; Huber, S.; Rust, P.; Streiff, A. B.; Zhang, Q.; Bode, J. W.; Piel, J. external pageWidespread Microbial Utilization of Ribosomal β-Amino Acid-Containing Peptides and Proteins.call_made Chem 2022, 8, 2659–2677.
(201) Kumarswamyreddy, N.; Nakagawa, A.; Endo, H.; Shimotohno, A.; Torii, K. U.; Bode, J. W.; Oishi, S. external pageChemical Synthesis of the EPF-Family of Plant Cysteine-Rich Proteins and Late-Stage Dye Attachment by Chemoselective Amide-Forming Ligations.call_made RSC Chem. Biol. 2022. https://doi.org/10.1039/D2CB00155A.
(200) Levasseur, M. D.; Hofmann, R.; Edwardson, T. G. W.; Hehn, S.; Thanaburakorn, M.; Bode, J. W.; Hilvert, D. external pagePost-Assembly Modification of Protein Cages by Ubc9-Mediated Lysine Acylation.call_made ChemBioChem 2022, e202200332.
(199) Nakamuro, T.; Kamei, K.; Sun, K.; Bode, J. W.; Harano, K.; Nakamura, E. external pageTime-Resolved Atomistic Imaging and Statistical Analysis of Daptomycin Oligomers with and without Calcium Ions.call_made J. Am. Chem. Soc. 2022, 144, 13612–13622.
- Preprint: external pagedoi.org/10.26434/chemrxiv-2022-xdkxs-v2call_made
(198) Tolmachova, K. A.; Farnung, J.; Liang, J. R.; Corn, J. E.; Bode, J. W. external pageFacile Preparation of UFMylation Activity-Based Probes by Chemoselective Installation of Electrophiles at the C-Terminus of Recombinant UFM1.call_made ACS Cent. Sci. 2022, 8, 756–762.
(197) Kumarswamyreddy, N.; Reddy, D. N.; Robkis, D. M.; Kamiya, N.; Tsukamoto, R.; Kanaoka, M. M.; Higashiyama, T.; Oishi, S.; Bode, J. W. external pageChemical Synthesis of Torenia Plant Pollen Tube Attractant Proteins by KAHA Ligation.call_made RSC Chem. Biol. 2022, 3, 721–727.
(196) Akimoto, G.; Fernandes, A. P.; Bode, J. W. external pageSite-Specific Protein Ubiquitylation Using an Engineered, Chimeric E1 Activating Enzyme and E2 SUMO Conjugating Enzyme Ubc9.call_made ACS Cent. Sci. 2022, 8, 275–281.
(195) Škopić, M. K.; Losch, F.; McMillan, A. E.; Willeke, N.; Malenica, M.; Bering, L.; Bode, J.; Brunschweiger, A. external pageReagent-Based Scaffold Diversity for DNA-Encoded Library Design: Solid Phase Synthesis of DNA-Tagged Sp3-Rich Heterocycles by SnAP Chemistry.call_made Org. Lett. 2022, 24, 1383–1387.
(194) Tung, P.; Schuhmacher, A.; Schilling, P. E.; Bode, J. W.; Mankad, N. external pagePreparation of Potassium Acyltrifluoroborates (KATs) from Carboxylic Acids by Copper-Catalyzed Borylation of Mixed Anhydrides.call_made Angew. Chem. Int. Ed. 2022, 61, e202114513.
- Preprint: external pagedoi.org/10.26434/chemrxiv-2021-jt414call_made
(193) Müller, M.; Gräbnitz, F.; Barandun, N.; Shen, Y.; Wendt, F.; Steiner, S. N.; Severin, Y.; Vetterli, S. U.; Mondal, M.; Prudent, J. R.; Hofmann, R.; van Oostrum, M.; Sarott, R. C.; Nesvizhskii, A. I.; Carreira, E. M.; Bode, J. W.; Snijder, B.; Robinson, J. A.; Loessner, M. J.; Oxenius, A.; Wollscheid, B. external pageLight-Mediated Discovery of Surfaceome Nanoscale Organization and Intercellular Receptor Interaction Networks.call_made Nat. Commun. 2021, 12, 7036.
- Preprint: external pagedoi.org/10.1101/2020.08.11.246652call_made
(192) Tanriver, M.; Dzeng, Y.-C.; Da Ros, S.; Lam, E.; Bode, J. W. external pageMechanism-Based Design of Quinoline Potassium Acyltrifluoroborates for Rapid Amide-Forming Ligations at Physiological pHcall_made. J. Am. Chem. Soc. 2021, 143, 17557–17565.
- Preprint: external pagedoi.org/10.26434/chemrxiv.14474166.v1call_made
(191) Farnung, J.; Song, H.; Bode, J. W. external pageChemical Protein Synthesis by Chemoselective #x03B1;-Ketoacid–Hydroxylamine (KAHA) Ligations with 5-Oxaprolinecall_made. In: Hussein W.M., Stephenson R.J., Toth I. (eds) Peptide Conjugation. Methods in Molecular Biology, vol 2355. Humana, New York, NY, 2021; pp 151–162.
(190) Fracassi, A.; Ray, A.; Nakatsuka, N.; Passiu, C.; Tanriver, M.; Schauenburg, D.; Scherrer, S.; Ouald Chaib, A.; Mandal, J.; N. Ramakrishna, S.; W. Bode, J.; D. Spencer, N.; Rossi, A.; Yamakoshi, Y. external pageKAT Ligation for Rapid and Facile Covalent Attachment of Biomolecules to Surfaces.call_made 2021, ASAP article
(189) Bhatt, P. R.; Scaiola, A.; Loughran, G.; Leibundgut, M.; Kratzel, A.; Meurs, R.; Dreos, R.; O’Connor, K. M.; McMillan, A.; Bode, J. W.; Thiel, V.; Gatfield, D.; Atkins, J. F.; Ban, N. external pageStructural Basis of Ribosomal Frameshifting during Translation of the SARS-CoV-2 RNA Genome.call_made Science 2021, eabf3546.
- Preprint: external pagedoi.org/2020.10.26.355099call_made
- Highlighted in ETH News
(188) Jiang, T.; Bordi, S.; McMillan, A. E.; Chen, K.-Y.; Saito, F.; Nichols, P. L.; Wanner, B. M.; Bode, J. W. external pageAn Integrated Console for Capsule-Based, Automated Organic Synthesis.call_made Chem. Sci. 2021, 12, 6977-6982.
- Preprint: external pagedoi.org/10.26434/chemrxiv.7882799.v1call_made
- Preprint highlighted in external pageNaturecall_made 2019, 568, 577-579.
(187) Matabaro, E.; Kaspar, H.; Dahlin, P.; Bader, D. L. V.; Murar, C. E.; Staubli, F.; Field, C. M.; Bode, J. W.; Künzler, M. external pageIdentification, heterologous production and bioactivity of lentinulin A and dendrothelin A, two natural variants of backbone N-methylated peptide macrocycle omphalotin A.call_made Sci. Rep. 2021, 11, 3541.
(186) Schuhmacher, A.; Ryan, S. J.; Bode, J. W. external pageCatalytic Synthesis of Potassium Acyltrifluoroborates (KATs) from Boronic Acids and the Thioimidate KAT Transfer Reagent.call_made Angew. Chem. Int. Ed. 2021, 60, 3918–3922.
(185) Jackl, M. K.; Gordon, C. P.; Copéret, C.; Bode, J. W. external pageSpirocyclic Nitroxide Biradicals: Synthesis and Evaluation as Dynamic Nuclear Polarizing Agents.call_made Helv. Chim. Acta 2020, 3, e2000179.
(184) Song, H.; Wu, D.; Mazunin, D.; Liu, S.M.; Sato, Y.; Broguiere, N.; Zenobi-Wong, M.; Bode, J..W.; external page"Post‐assembly Photomasking of Potassium Acyltrifluoroborates (KATs) for Two‐Photon 3D Patterning of PEG‐Hydrogels"call_made, Helv. Chim. Acta. 2020, 103, e2000172.
(183) Hofmann, R.; Akimoto, G.; Wucherpfennig, T. G., Zeymer, C., Bode, J. W.;external page"Lysine Acylation Using Conjugating Enzymes (LACE) for Site-Specific Modification and Ubiquitination of Native Proteins"call_made, Nat. Chem. 2020, 12, 1008–1015.
- highlighted in external pageNat. Chem.call_made 2020, 12, 980-982.
- cover picture external pageNat. Chem.call_made 2020, 12(11).
(182) Weidner, P.; Söhn, M.; Schroeder, T.; Helm, L.; Hauber, V.; Gutting, T.; Betge, J.; Röcken, C.; Rohrbacher, F. N.; Pattabiraman, V. R.; Bode, J. W.; Seger, R.; Saar, D.; Nunes-Alves, A.; Wade, R. C.; Ebert, M. P. A.; Burgermeister, E.; external pageMyotubularin-Related Protein 7 Activates Peroxisome Proliferator-Activated Receptor-Gammacall_made, Oncogenesis 2020, 9, 59.
(181) Wu, D.; Taguchi, J.; Tanriver, M.; Bode, J..W.; external pageSynthesis of Acylboron Compoundscall_made. Angew. Chem. Int. Ed. 2020, 59, 16847–16858.
(180) Osuna Gálvez, A.; Bode, J. W.; external page"Synthesis of Amides from Acylboron Compounds"call_made Science of Synthesis Knowledge Updates 2020, 1, 375.
(179) Broguiere, N.; Lüchtefeld, I.; Trachsel, L.; Mazunin, D.; Rizzo, R.; Bode, J. W.; Lutolf, M. P.; Zenobi‐Wong, M.; external page"Morphogenesis Guided by 3D Patterning of Growth Factors in Biological Matrices"call_made Adv. Mater. 2020, 1908299.
(178) Schauenburg, D.; Divandari, M.; Neumann, K.; Spiegel, C.A.; Hackett, T.; Dzeng, Y.; Spencer, N.D.; Bode, J..W.; external page"Synthesis of polymers containing potassium acyltrifluoroborates (KATs) and post‐polymerization ligation and conjugation"call_made Angew. Chem. Int. Ed. 2020, 59, 14656–14663.
(177) Schuhmacher, A.; Shiro, T.; Ryan, S. J.; Bode, J. W.; external page"Synthesis of secondary and tertiary amides without coupling agents from amines and potassium acyltrifluoroborates (KATs)"call_made Chem. Sci. 2020, 11, 7609.
(176) Neumann, K.; Farnung, J.; Baldauf, S.; Bode, J. W.; external page"Prevention of aspartimide formation during peptide synthesis using cyanosulfurylides as carboxylic acid-protecting groups"call_made Nat. Commun. 2020, 11, 982.
(175) Murar, C. E.; Ninomiya, M.; Shimura, S.; Karakus, K.; Boyman, O.; Bode, J. W.; external page"Chemical Synthesis of Interleukin‐2 and Disulfide Stabilizing Analogues"call_made Angewandte Chem. Int. Ed. 2020, 59, 8425–8429.
(174) Stepek, I., A.; Hofmann, R.; Nichols, P.; Aschwanden, A.; Eckhard, C.; Aschwanden, P.; Bode, J. W.; "external pageMake a Molecule: A Synthetic Organic and Medicinal Chemistry Workshop Program for High School Studentscall_made" J. Chem. Educ. 2020, 2, 402-413.
(173) Baldauf, S.; Ogunkoya, A. O.; Boross, G. N.; Bode, J. W.; "external pageAspartic Acid Forming α-Ketoacid–Hydroxylamine (KAHA) Ligations with (S)-4,4-difluoro-5-oxaprolinecall_made" J. Org. Chem. 2020, 3, 1352-1364.
(172) Chiotellis, A.; Ahmed, H.; Betzel, T.; Tanriver, M.; White, C. J.; Song, H.; Da Ros, S.; Schibli, R.; Bode, J. W.; Ametamey, S. M.; "external pageChemoselective 18F-incorporation into pyridyl acyltrifluoroborates for rapid radiolabelling of peptides and proteins at room temperaturecall_made" Chem. Commun. 2020, 56, 723-726.
(171) Zhang, Y.; Hirota, T.; Kuwata, K.; Oishi, S.;Gramani, S.G.; Bode, J.W.; external page"Chemical Synthesis of Atomically Tailored SUMO E2 Conjugating Enzymes for the Formation of Covalently Linked SUMO–E2–E3 Ligase Ternary Complexes"call_made J. Am. Chem. Soc. 2019, 141, 14742-14751.
(170) Baldauf, S.; Schauenburg, D.; Bode, J. W.; external page"A threonine‐forming oxazetidine amino acid for the chemical synthesis of proteins with the KAHA ligation"call_made Angew. Chem. Int. Ed. 2019, 58, 1–6.
(169) Wang, Y.; Bode, J. W.; external page"Olefin Amine (OLA) Reagents for the Synthesis of Bridged Bicyclic and Spirocyclic Saturated N-Heterocycles by Catalytic HAT Reactions"call_made J. Am. Chem. Soc. 2019, 141, 9739-9745.
(168) Osuna Gálvez, A.; Bode, J. W.; external page"Traceless Templated Amide-Forming Ligations"call_made J. Am. Chem. Soc. 2019, 141, 8721-8726.
(167) Wu, D.; Fohn, N. A.; Bode, J. W.; external page"Catalytic Synthesis of Potassium Acyltrifluoroborates (KATs) byChemoselective Cross-Coupling with a Bifunctional Reagent"call_made Angew. Chem. Int. Ed. 2019, 58, 11058-11062.
(166) Stepek, I. A.; Cao, T.; Koetemann, A.; Shimura, S.; Wollscheid, B.; Bode, J. W. external page"Antibiotic discovery with synthetic fermentation: library assembly, phenotypic screening, and mechanism of action of beta-peptides targeting penicillin-binding proteins"call_made ACS Chem. Biol. 2019, 14, 1030-1040
(165) Saito, F.; Trapp, N.; Bode, J. W. external page"Iterative Assembly of Polycyclic Saturated Heterocycles from Monomeric Building Blocks"call_made J. Am. Chem. Soc. 2019, 141, 5544–5554
(164) Luescher, M. U.; Bode, J. W. external page"Evidence for a Radical Mechanism in Cu(II)-Promoted SnAP Reactions"call_made Synlett 2019, 30, A–G
(163) Book: Pattabiraman, V. R.; Ogunkoya, A. O.; Bode, J. W. external page"Amide-Forming Ligation Reactions"call_made Organic Reactions (Vol. 97) [Ed: Scott E. Denmark et al.], John Wiley & Sons, Inc.
(162) Baldauf, S.; Bode, J. W. external page"Synthesis and Evaluation of Cyclic Acetals of Serine Hydroxylamine for Amide-Forming KAHA Ligations"call_made Synthesis 2019, 51, A-K
(161) Boross, G. N.; Schauenburg, D.; Bode, J. W. external page"Chemoselective derivatization of folded synthetic insulin variants with potassium acyltrifluoroborates (KATs)"call_made Helv. Chim. Acta 2019, 102, e1800214.
(160) Vagstad, A. L.; Kuranaga, T.; Püntener, S.; Pattabiraman, V. R.; Bode, J. W.; Piel, J. external page"Introduction of D‐Amino Acids in Minimalistic Peptide Substrates by an S‐Adenosyl‐L‐Methionine Radical Epimerase"call_made Angew. Chem. Int. Ed. 2018, 58, 2246-2250
(159) Gu, Y.; Schauenburg, D.; Bode, J. W.; Johnson, J. A. external page"Leaving Groups as Traceless Topological Modifiers for the Synthesis of Topologically Isomeric Polymer Networks"call_made J. Am. Chem. Soc. 2018, 140, 14033–14037
(158) Luescher, M. U.; Jindakun, C.; Bode, J. W. external page"Stannylamine Protocol (SnAP) Reagents for the Synthesis of C–Substituted Morpholines from Aldehydes"call_made Org. Synth. 2018, 95, 357-373
(157) Luescher, M. U.; Jindakun, C.; Bode, J. W. external page"Preparation of Tributyl(iodomethyl)stannane"call_made Org. Synth. 2018, 95, 345-356
(156) Boross, G. N.; Shimura, S.; Besenius, M.; Tennagels, N.; Rossen, K.; Wagner, M.; Bode, J. W. external page"Facile folding of insulin variants bearing a prosthetic C-peptide prepared by α-ketoacid-hydroxylamine (KAHA) ligation"call_made Chem. Sci. 2018, 9, 8388-8395
(155) Murar, C. E.; Harmand, T. J.; Takano, H.; Bode, J. W. external page"Preparation of (S)-N-Boc-5-oxaproline"call_made Org. Synth. 2018, 95, 157-176
(154) Harmand, T. J.; Murar, C. E.; Takano, H.; Bode, J. W. external page"Enantioselective Synthesis of (S)-Ethyl 2-((tert-butoxycarbonyl)((tert-butyldimethylsilyl)oxy)amino)-4-oxobutanoate"call_made Org. Synth. 2018, 95, 142-156
(153) Schauenburg, D.; Osuna Gálvez, A.; Bode, J. W. external page"Covalently functionalized amide-crosslinked hydrogels from primary amines and polyethylene glycol acyltrifluoroborates (PEG-KATs)"call_made J. Mater. Chem. B
2018, 6, 4775-4782
(152) Jackl, M.; Schuhmacher, A.; Shiro, T.; Bode, J. W.; external page"Synthesis of N,N-Alkylated α-Tertiary Amines by Coupling of α-Aminoalkyltrifluoroborates and Grignard Reagents"call_made Org. Lett. 2018, 20, 4044–4047
(151) Shiro, T.; Schuhmacher, A.; Jackl, M.; Bode, J. W.; external page"Facile Synthesis of α-Aminoboronic Acids from Amines and Potassium Acyltrifluoroborates (KATs) via Trifluoroborate-Iminiums (TIMs)"call_made Chem. Sci. 2018, 9, 5191-5196
- external pagereviewedcall_made in Synfacts 2018, 14, 855
(150) Rohrbacher, F.; Zwicky, A.; Bode, J. W.; external page"Facile Synthesis of Internal and C-Terminal Peptide α-Ketoamides with Fmoc-Solid Phase Peptide Synthesis"call_made Helv. Chim. Acta 2018, 101, e1800039
(149) Review article: Stepek, I. A.; Bode, J. W.; external page"Synthetic fermentation of bioactive molecules"call_made Curr. Opin. Chem. Biol. 2018, 46, 18–24
(148) Liu, S. M.; Wu, D.; Bode, J. W.; external page"One-Step Synthesis of Aliphatic Potassium Acyltrifluoroborates (KATs) from Organocuprates"call_made Org. Lett. 2018, 20, 2378–2381
(147) Jindakun, C.; Hsieh, S.-Y.; Bode, J. W.; external page"Iridium-catalyzed Synthesis of Saturated N‐Heterocycles from Aldehydes and SnAP Reagents with Continuous Flow Photochemistry"call_made Org. Lett. 2018, 20, 2071–2075
- external pagereviewedcall_made in Synfacts 2018, 12, 629
(146) Hubert, J. G.; Stepek, I. A.; Noda, H.; Bode, J. W.; external page"Synthetic Fermentation of β-peptide Macrocycles by Thiadiazole-Forming Ring-Closing Reactions"call_made Chem. Sci. 2018, 9, 2159–2167
- external pagehighlightedcall_made in Chimia 2018, 72, 338
(145) White, C. J.; Bode, J. W.; external page"PEGylation and Dimerization of Expressed Proteins under Near Equimolar Conditions with Potassium 2-Pyridyl Acyltrifluoroborates"call_made ACS Cent. Sci. 2018, 4, 197–206
(144) Luescher, M. U.; Songsichan, T.; Hsieh, S.-Y.; Bode, J. W.; external page"Copper Promoted Oxidative Coupling of SnAP Hydrazines and Aldehydes to Form Chiral 1,4,5-Oxadiazepanes and 1,2,5-Triazepanes"call_made Helv. Chim. Acta 2017, 100, e1700199
(143) Taguchi, J.; Ikeda, T.; Takahashi, R.; Sasaki, I.; Ogasawara, Y.; Dairi, T.; Kato, N.; Yamamoto, Y.; Bode, J. W.; Ito, H. external page"Synthesis of Acylborons by Ozonolysis of Alkenylboronates: Preparation of an Enantioenriched Amino Acid Acylboronate"call_made Angew. Chem. Int. Ed. 2017, 56, 13847–13851external pagecall_made
(142) Bode, J. W. external page"Chemical Protein Synthesis with the α-Ketoacid–Hydroxylamine Ligation"call_made Acc. Chem. Res. 2017, 50, 2104–2115
(141) Harmand, T. J.; Pattabiraman, V. R.; Bode, J. W. external page"Chemical Synthesis of the Highly Hydrophobic Antiviral Membrane Associated Protein IFITM3 and Modified Variants"call_made Angew. Chem. Int. Ed. 2017, 56, 12639–12643
(140) Jackl, M. K.; Legnani, L.; Morandi, B.; Bode, J. W. external page"Continuous Flow Synthesis of Morpholines and Oxazepanes with Silicon Amine Protocol (SLAP) Reagents and Lewis Acid Facilitated Photoredox Catalysis"call_made Org. Lett., 2017, 19, 4696–4699
- external pagehighlightedcall_made in Org. Process Res. Dev. 2017, 21, 1453–1463
(139) Rohrbacher, F.; Baldauf, S.; Wucherpfennig, T. G.; Bode, J. W. external page"Product Selectivity in KAHA Ligations: Ester vs. Amide Formation with Cyclic Hydroxylamines"call_made Synlett. 2017, 28, 1929–1933
(138) Murar, C. E.; Harmand, T. J.; Bode, J. W. external page"Improved synthesis of (S)-N-Boc-5-oxaproline for protein synthesis with the α-ketoacid-hydroxylamine (KAHA) ligation"call_made Bioorg. Med. Chem. 2017, 25, 4996–5001
(137) Rohrbacher, F.; Zwicky, A.; Bode, J. W. external page"Chemical Synthesis of a Homoserine-Mutant of the Antibacterial, Head-to-Tail Cyclized Protein AS-48 by α-Ketoacid–Hydroxylamine (KAHA) Ligation"call_made Chem. Sci. 2017, 8, 4051–4055
(136) Saito, F.; Bode, J. W. external page"Synthesis and stabilities of peptide-based [1]rotaxanes: molecular grafting onto lasso peptide scaffolds"call_made Chem. Sci. 2017, 8, 2878–2884
(135) Osuna Gálvez, A.; Schaack, C. P.; Noda, H.; Bode, J. W. external page"Chemoselective acylation of primary amines and amides with potassium acyltrifluoroborates under acidic conditions"call_made J. Am. Chem. Soc. 2017, 139, 1826–1829
- external pagehighlightedcall_made in Org. Process Res. Dev. 2017, 21, 279–291
(134) Oriana, S.; Ye, C.; Bode, J. W.; Yamakoshi, Y. external page"Synthesis of tri-functionalized MMP2 FRET probes using a chemo-selective and late-stage modification of unprotected peptides"call_made Org. Biomol. Chem. 2017, 15, 1792-1800
(133) Hsieh, S-.Y.; Bode, J. W. external page"Lewis Acid Induced Toggle from Ir(II) to Ir(IV) Pathways in Photocatalytic Reactions: Synthesis of Thiomorpholines and Thiazepanes from Aldehydes and SLAP Reagents"call_made ACS Cent. Sci. 2017, 3, 66–72
(132) Mazunin, D.; Bode, J. W. external page"Potassium Acyltrifluoroborate (KAT) Ligations are Orthogonal to Thiol-Michael and SPAAC Reactions: Covalent Dual Immobilization of Proteins onto Synthetic PEG Hydrogels"call_made Helv. Chim. Acta 2017, 100, e1600311
(131) Kreituss, I.; Bode, J. W. external page"Flow chemistry and polymer-supported pseudoenantiomeric acylating agents enable parallel kinetic resolution of chiral saturated N-heterocycles"call_made Nature Chem. 2017, 9, 446–452
(130) Kreituss, I.; Bode, J. W. external page"Catalytic Kinetic Resolution of Saturated N-Heterocycles by Enantioselective Amidation with Chiral Hydroxamic Acids"call_made Acc. Chem. Res. 2016, 49, 2807–2821
(129) Book chapter: Chiang, P.-C.; Bode, J. W. external page"N-Heterocyclic Carbenes as Organic Catalysts"call_made N-Heterocyclic Carbenes: From Laboratory Curiosities to Efficient Synthetic Tools (Edition 2) [Ed: Silvia Diez-Gonzalez]
(128) Perspective: Saito, F.; Bode, J. W. "external pageMacrocyclic Peptides: Tying Up Loose Endscall_made" Nature Chem. 2016, 8, 1085-1086
(127) Perspective: Hofmann, R.; Bode, J. W. external page"A Radical Approach to Posttranslational Mutagenesis"call_made Science 2016, 354, 553–554.
(126) Liu, S. M.; Mazunin, D.; Pattabiraman, V. R.; Bode, J. W. external page"Synthesis of Bifunctional Potassium Acyltrifluoroborates"call_made Org. Lett. 2016, 18, 5336–5339
(125) Thuaud, F.; Rohrbacher, F.; Zwicky, A.; Bode, J. W. external page"Photoprotected Peptideα-Ketoacids and Hydroxylamines for Iterative and One-Pot KAHA Ligations: Synthesis of NEDD8"call_made Helv. Chim. Acta 2016, 99, 868–894
(124) Trindade, A. F.; Bode, J. W. external page"Irreversible Conjugation of Aldehydes in Water To Form Stable 1,2,4-Oxadiazinan-5-ones"call_made Org. Lett. 2016, 18, 4210–4213
(123) Wucherpfennig, T. G.; Müller, S; Wolfrum, C.; Bode, J. W. external page"Chemical Synthesis of the 12 kDa Human Myokine Irisin byα-Ketoacid-Hydroxylamine (KAHA) Ligation"call_made Helv. Chim. Acta 2016, 99, 897–907
(122) Thuaud, F.; Rohrbacher, F.; Zwicky, A.; Bode, J. W. external page"Incorporation of Acid-Labile Masking Groups for the Traceless Synthesis of C-Terminal Peptide α-Ketoacids"call_made Org. Lett. 2016, 18, 3670–3673
(121) Harmand, T. J.; Murar, C. E.; Bode, J. W. external page"Protein chemical synthesis by α-ketoacid-hydroxylamine ligation"call_made Nature Protocols 2016, 11, 1130-1147
(120) Luescher, M. U.; Bode, J. W.; external page"SnAP-eX Reagents for the Synthesis of Exocyclic 3-Amino- and 3-Alkoxypyrrolidines and Piperidines from Aldehydes"call_made Org. Lett. 2016, 18, 2652–2655
(119) Hsieh, S.-Y.; Bode, J. W.; external page"Silicon Amine Reagents for the Photocatalytic Synthesis of Piperazines from Aldehydes and Ketones"call_made Org. Lett. 2016, 18, 2098–2101
(118) Jackl, M. K.; Kreituss, I.; Bode J. W.; external page"Synthesis of Tetrahydronaphthyridines from Aldehydes and HARP Reagents via Radical Pictet–Spengler Reactions"call_made Org. Lett. 2016, 18, 1713–1715
- external pagereviewedcall_made in Synfacts 2016, 12, 0569
(117) Kreituss, I.; Chen, K.-Y.; Eitel, S. H.; Adam, J.-M.; Wuitschik, G.;Fettes, A.; Bode, J. W. external page"A Robust, Recyclable Resin for Decagram Scale Resolution of (±)-Mefloquine and Other Chiral N-Heterocycles"call_made Angew. Chem. Int. Ed. 2016, 55, 1553–1556.
- external pagereviewedcall_made in Synfacts 2016, 12, 0422.
(116) Account: Noda, H.; Bode, J. W. external page"Synthesis and Reactivities of Monofluoro Acylboronates in Chemoselective Amide Bond Forming Ligation with Hydroxylamines"call_made Org. Biomol. Chem. 2016, 14, 16–20.
(115) He, C.; Kulkarni, S. S.; Thuaud, F.; Bode, J. W. external page"Chemical Synthesis of the 20 kDa Heme Protein Nitrophorin 4 by α-Ketoacid-Hydroxylamine (KAHA) Ligation"call_made Angew. Chem. Int. Ed. 2015, 54, 12996–13001.
(114) Wanner, B.; Kreituss, I.; Gutierrez, O.; Kozlowski, M. C.; Bode, J. W. external page"Catalytic Kinetic Resolution of Disubstituted Piperidines by Enantioselective Acylation: Synthetic Utility and Mechanistic Insights"call_made J. Am. Chem. Soc. 2015, 137, 11491–11497.
(113) Review article: Luescher, M. U.; Geoghegan, K.; Nichols, P. L.; Bode, J. W. external page"SnAP Reagents for a Cross-Coupling Approach to the One-Step Synthesis of Saturated N-Heterocycles"call_made, Aldrichim. Acta 2015, 48, 43–48.
(112) Luescher, M. U.; Bode, J. W. external page"Catalytic Synthesis of N-Unprotected Piperazines, Morpholines, and Thiomorpholines from Aldehydes and SnAP Reagents"call_made Angew. Chem. Int. Ed. 2015, 54, 10884–10888.
- SnAP reagents are commercially available on external pageSIGMA-ALDRICHcall_made!
(111) Pusterla, I.; Bode, J. W. external page"An oxazetidine amino acid for chemical protein synthesis by rapid, serine-forming ligations"call_made Nature Chem. 2015, 7, 668–672.
- external pagereviewedcall_made in Synform 2016, 02, A29-A31
(110) Rohrbacher, F.; Deniau, G.; Luther, A.; Bode, J. W. external page"Spontaneous Head-to-Tail Cyclization of Unprotected Linear Peptides with the KAHA Ligation"call_made Chem. Sci. 2015, 6, 4889–4896.
(109) Mazunin, D.; Broguiere, N.; Zenobi-Wong, M.; Bode, J. W. external page"Synthesis of Biocompatible PEG Hydrogels by pH-Sensitive Potassium Acyltrifluoroborate (KAT) Amide Ligations"call_made ACS Biomater. Sci. Eng. 2015, 1, 456–462.
(108) Geoghegan, K.; Bode, J. W. external page"Bespoke SnAP Reagents for the Synthesis of C-Substituted Spirocyclic and Bicyclic Saturated N-Heterocycles"call_made Org. Lett. 2015, 17, 1934–1937.
- SnAP reagents are commercially available on external pageSIGMA-ALDRICHcall_made!
(107) Book chapter: Rohrbacher, F.; Wucherpfennig, T. G.; Bode, J. W. external page"Chemical Protein Synthesis with the KAHA Ligation"call_made Top. Curr. Chem. 2015, 363, 1–32.
(106) Noda, H.; Bode, J. W. external page"Synthesis of Chemically and Configurationally Stable Monofluoro Acylboronates: Effect of Ligand Structure on their Formation, Properties and Reactivities"call_made J. Am. Chem. Soc. 2015, 137, 3958–3966.
(105) Harmand, T. J.; Kulkarni, S. S.; Bode, J. W. external page"Optimized Synthesis of a Cyanosulfurylide Linker for Fmoc-SPPS of C-Terminal Peptide α-Ketoacids"call_made Tetrahedron Lett. 2015, 56, 3477–3480.
(104) Saito, F.; Noda, H.; Bode, J. W. external page"Critical evaluation and rate constants of chemoselective ligation reactions for stoichiometric conjugations in water"call_made ACS Chem. Biol. 2015, 10, 1026–1033.
- external pagehighlightedcall_made in Nat. Chem. Biol. 2015, 11, 241.
(103) Schäfer, G.; Leu, L.; Bode, J. W. external page"Synthesis of Unsymmetrical,gem-Disubstituted Bisamides"call_made Heterocycles 2015, 90, 1375–1386. (Special issue)
- Dedicated to Professor Isao Kuwajima on the occasion of his 77th birthday.
(102) Murar, C. E.; Thuaud, F.; Bode, J. W. external page"KAHA Ligations that form Aspartyl Aldehyde Residues as Synthetic Handles for Protein Modification and Purification"call_made J. Am. Chem. Soc. 2014, 136, 18140–18148.
(101) Siau, W.-Y.; Bode, J. W. external page"One Step Synthesis of Saturated Spirocyclic N-Heterocycles with SnAP Reagents and Ketones"call_made J. Am. Chem. Soc. 2014, 136, 17726–17729.
- SnAP reagents are commercially available on external pageSIGMA-ALDRICHcall_made!
(100) Review article: Harmand, T. J. R.; Murar, C. E.; Bode, J. W. external page"New chemistries for chemoselective peptide ligations and the total synthesis of proteins"call_made Curr. Opin. Chem. Biol. 2014, 22, 115–121.
(99) Wucherpfennig, T. G.; Pattabiraman, V. R.; Limberg, F. R. P.; Ruiz-Rodríguez, J.; Bode, J. W. external page"Traceless Preparation of C-Terminal α-Ketoacids for Chemical Protein Synthesis by α-Ketoacid–Hydroxylamine Ligation: Synthesis of SUMO2/3"call_made Angew. Chem. Int. Ed. 2014, 53, 12248–12252.
(98) Wucherpfennig, T. G.; Rohrbacher, F.; Pattabiraman, V. R.; Bode, J. W. external page"Formation and Rearrangement of Homoserine Depsipeptides and Depsiproteins in the α-Ketoacid–Hydroxylamine Ligation with 5-Oxaproline"call_made Angew. Chem. Int. Ed. 2014, 53, 12244–12247.
- selected as a Hot Paper.
(97) Huang, Y.-L.; Bode, J. W. external page"Synthetic fermentation of bioactive non-ribosomal peptides without organisms, enzymes or reagents"call_made Nature Chem. 2014, 6, 877–884.
- external pagehighlightedcall_made in C&EN.
- external pagehighlightedcall_made in Chemistry World.
- external pageInterviewcall_made: Nature Chem. 2014, 6, 846–847.
- external pagehighlightedcall_made in Nat. Chem. Biol. 2014, 10, 984.
(96) Allen, S. E.; Hsieh, S.-Y.; Gutierrez, O.; Bode, J. W.; Kozlowski, M. C. external page"Concerted Amidation of Activated Esters: Reaction Path and Origins of Selectivity in the Kinetic Resolution of Cyclic Amines via NHC and Hydroxamic Acid Co-Catalyzed Acyl Transfer"call_made J. Am. Chem. Soc. 2014, 136, 11783–11791.
(95) Erős, G.; Kushida, Y.; Bode, J. W. external page"A Reagent for the One-Step Preparation of Potassium Acyltrifluoroborates (KATs) from Aryl- and Heteroarylhalides"call_made Angew. Chem. Int. Ed. 2014, 53, 7604–7607.
- selected as a Hot Paper.
- external pagereviewedcall_made in Synfacts 2014, 10, 1071.
(94) Hsieh, S.-Y.; Bode, J. W. external page"(4aR,9aS)-4-Hydroxy-4,4a,9,9a-tetrahydroindeno[2,1-b][1,4]oxazin-3(2H)-one"call_made e-EROS 2014, Published Online. (DOI: 10.1002/047084289X.rn01654)
(93) Noda, H.; Bode, J. W. external page"Synthesis and Chemoselective Ligations of MIDA Acylboronates withO-Me Hydroxylamines"call_made Chem. Sci. 2014, 5, 4328–4332.
(92) Hsieh, S.-Y.; Wanner, B.; Wheeler, P.; Beauchemin, A. M.; Rovis, T; Bode, J. W. external page"Stereoelectronic Basis for the Kinetic Resolution of N-Heterocycles with Chiral Acylating Reagents"call_made Chem. Eur. J. 2014, 20, 7228–7231.
(91) Schäfer, G.; Bode, J. W. external page"The Synthesis of Sterically Hindered Amides"call_made CHIMIA 2014, 68, 252–255.
- On the occasion of the SCS-Metrohm Foundation Award for best oral presentation at the Fall Meeting 2013.
(90) Noda, H; Erős, G; Bode, J. W. external page"Rapid Ligations with Equimolar Reactants in Water with the Potassium Acyltrifluoroborate (KAT) Amide-Formation"call_made J. Am. Chem. Soc. 2014, 136, 5611–5614.
- external pagehighlightedcall_made in C&EN.
(89) Review article: Vo, C.-V.; Bode, J. W. external page"Synthesis of Saturated N-Heterocycles"call_made J. Org. Chem. 2014, 79, 2809–2815.
- SnAP reagents are commercially available on external pageSIGMA-ALDRICHcall_made!
(88) Schäfer, G.; Bode, J. W. external page"Synthesis of Sterically HinderedN-Acylated Amino Acids fromN-Carboxyanhydrides"call_made Org. Lett. 2014, 16, 1526–1529.
- external pagereviewedcall_made in Synfacts 2014, 10, 635.
- external pagehighlightedcall_made in Org. Process Res. Dev. 2014, 18, 562–572.
(87) Vo, C.-V.; Luescher, M. U.; Bode, J. W. external page"SnAP Reagents for the One-Step Synthesis of Medium Ring Saturated N-Heterocycles from Aldehydes"call_made Nature Chem. 2014, 6, 310–314.
- external pagehighlightedcall_made in C&EN.
- external pagehighlightedcall_made in CHIMIA.
- external pagehighlightedcall_made in Synfacts 2014, 10, A108.
- SnAP reagents are commercially available on external pageSIGMA-ALDRICHcall_made!
(86) Luescher, M. U.; Vo, C.-V.; Bode, J. W. external page"SnAP Reagents for the Synthesis of Piperazines and Morpholines"call_made Org. Lett. 2014, 16, 1236–1239.
- external pagehighlightedcall_made in C&EN.
- external pageabstractedcall_made in ChemInform 2014, published online. (DOI: 10.1002/chin.201432028)
- SnAP reagents are commercially available on external pageSIGMA-ALDRICHcall_made!
(85) Review article: Mahatthananchai, J.; Bode, J. W. external page"On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums"call_made Acc. Chem. Res. 2014, 47, 696–707.
(84) Book chapter: Mahatthananchai, J.; Bode, J. W. external page"Catalytic Reactions with N-Mesityl Substituted N-Heterocyclic Carbenes"call_made Contemporary Carbene Chemistry 2013, 237–273. [Eds: Robert A. Moss / Michael P. Doyle]
(83) News and views: Bode, J. W. external page"Carbene catalysis: An internal affair"call_made Nature Chem. 2013, 5, 813–815.
(82) Teichert, J. F.; Mazunin, D.; Bode, J. W. external page"Chemical Sensing of Polyols with Shapeshifting Boronic Acids as a Self-Contained Sensor Array"call_made J. Am. Chem. Soc. 2013, 135, 11314–11321.
- external pagehighlightedcall_made in Spotlights on Recent JACS Publications, J. Am. Chem. Soc. 2013, 135, 11679–11679.
(81) Gondo, C. A.; Bode, J. W. external page"Catalytic Redox Amidations of Aldehydes with a Polymer-Supported Peptide-N-Heterocyclic Carbene Multifunctional Catalyst"call_made Synlett 2013, 24, 1205–1210.
- Cluster Issue on Carbene Catalysis
(80) Vo, C.-V.; Mikutis, G.; Bode, J. W. external page"SnAP Reagents for the Transformation of Aldehydes into Substituted Thiomorpholines—An Alternative to Cross-Coupling with Saturated Heterocycles"call_made Angew. Chem. Int. Ed. 2013, 52, 1705–1708.
- external pagehighlightedcall_made in C&EN.
- SnAP reagents are commercially available on external pageSIGMA-ALDRICHcall_made!
(79) He, M.; Bode, J. W. external page"E pluribus unum: Isolation, structure determination, network analysis and DFT studies of a single metastable structure from a shapeshifting mixture of 852 bullvalene structural isomers"call_made Org. Biomol. Chem. 2013, 11, 1306–1317.
- external pageselectedcall_made as a cover. Org. Biomol. Chem. 2013, 11, 1262.
(78) Chiang, Y.-L; Russak, J. A.; Carrillo, N; Bode, J. W. external page"Synthesis of Enantiopure Isoxazolidine Monomers for the Preparation of β3-Oligopeptides by Iterative α-Ketoacid–Hydroxylamine (KAHA) Ligations"call_made Helv. Chim. Acta 2012, 2481–2501.
- Dedicated to Professor Dieter Seebach on the occasion of his 75th birthday
(77) He, M.; Rommel, M.; Bode, J. W. external page"Formal Synthesis of (±)-Clausenamide by NHC-Catalyzed γ-Lactam Formation"call_made Heterocycles 2012, 86, 1689–1696. (Special issue)
(76) Book chapter: Mahatthananchai, J.; Bode, J. W. external page"Enantioselective Annulations With Chiral N-Mesityl N-Heterocyclic Carbenes"call_made Asymmetric Synthesis: The Essentials II, 2012, 67–77. [Eds: Christmann, Mathias / Bräse, Stefan]
(75) Review article: Mahatthananchai, J.; Dumas, A. M.; Bode, J. W. external page"Catalytic Selective Synthesis"call_made Angew. Chem. Int. Ed. 2012, 51, 10954–10990.
- Dedicated to Professor Michael P. Doyle on the occasion of his 70th birthday
- external pagehighlightedcall_made in Org. Process Res. Dev. 2013, 17, 160–168.
(74) Kreituss, I.; Murakami, Y.; Binanzer, M.; Bode, J. W. external page"Kinetic Resolution of Nitrogen Heterocycles with a Reusable Polymer-Supported Reagentcall_made" Angew. Chem. Int. Ed. 2012, 51, 10660–10663.
- external pagehighlightedcall_made in Org. Process Res. Dev. 2012, 16, 1674–1683.
(73) Book Chapter: Bode, J. W. external page"Reinventing Amide Bond Formation"call_made Top. Organomet. Chem. 2013, 44, 13–33.
(72) Ogunkoya, A. O.; Pattabiraman, V. R.; Bode, J. W. external page"Sequential α-Ketoacid-Hydroxylamine (KAHA) Ligations: Synthesis of C-Terminal Variants of the Modifier Protein UFM1"call_made Angew. Chem. Int. Ed. 2012, 51, 9693–9697.
- external pageCorrigendumcall_made: Angew. Chem. Int. Ed. 2014, 53, 12005.
(71) Kravina, A. G., Mahatthananchai, J.; Bode, J. W. external page"Enantioselective, NHC-Catalyzed Annulations of Trisubstituted Enals and Cyclic N-Sulfonylimines via α,β-Unsaturated Acyl Azoliums"call_made Angew. Chem. Int. Ed. 2012, 51, 9433–9436.
(70) Schäfer, G.; Matthey, C.; Bode, J. W. external page"Facile Synthesis of Sterically Hindered and Electron-Deficient Secondary Amides from Isocyanates"call_made Angew. Chem. Int. Ed. 2012, 51, 9173–9175.
- selected as a Hot Paper.
(69) Hsieh, S.-Y.; Binanzer, M.; Kreituss, I.; Bode, J. W. external page"Expanded substrate scope and catalyst optimization for the catalytic kinetic resolution of N-heterocycles"call_made Chem. Commun. 2012, 48, 8892–8894.
- external pageabstractedcall_made in ChemInform 2012, published online. (DOI: 10.1002/chin.201249022)
(68) Book chapter: Gondo, C. A.; Bode, J. W. "1,2,4-Triazolium Salts", Science of Synthesis: Houben Weyl Methods of Molecular Transformations, Vol. 13.33, 2012, Georg Thieme Verlag, 199–214. [Ed: B. List]
(67) Allen, S. E.; Mahatthananchai, J.; Bode, J. W.; Kozlowski, M. C. external page"Oxyanion-steering and CH-π Interactions as Key Elements in a N-Heterocyclic Carbene-Catalyzed [4+2] Cycloaddition"call_made J. Am. Chem. Soc. 2012, 134, 12098–12103
- external pagehighlightedcall_made in CHIMIA 2012, 66, 801.
(66) Dumas, A. M., Molander, G. A., Bode, J. W. external page"Amide-Forming Ligation of Acyltrifluoroborates and Hydroxylamines in Water"call_made Angew. Chem. Int. Ed. 2012, 51, 5683–5686.
(65) Dumas, A. M.; Bode, J. W. external page"Synthesis of Acyltrifluoroborates"call_made Org. Lett. 2012, 14, 2138–2141.
- external pagehighlightedcall_made in Org. Process Res. Dev. 2012, 16, 1244–1257.
(64) Lyngvi, E.; Bode, J. W.; Schoenebeck, F. external page"A Computational Study of the Origin of Stereoinduction in NHC-Catalyzed Annulation Reactions of alpha,beta-Unsaturated Acyl Azoliumscall_made" Chem. Sci. 2012, 3, 2346–2350.
(63) Larson, K. K.; He, M.; Teichert, J. F.; Naganawa, A.; Bode, J. W. external page"Chemical Sensing with Shapeshifting Organic Molecules"call_made Chem. Sci. 2012, 3, 1825–1828.
- external pagehighlightedcall_made in Nature Chem. 2012, 4, 336–337.
(62) Pattabiraman, V. R.; Ogunkoya, A. O.; Bode, J. W. external page"Chemical Protein Synthesis by Chemoselective α-Ketoacid–Hydroxylamine (KAHA) Ligations with 5-Oxaproline"call_made Angew. Chem. Int. Ed. 2012, 51, 5114–5118.
- external pageselectedcall_made as a Hot Paper & Cover.
- external pageCorrigendumcall_made: Angew. Chem. Int. Ed. 2014, 53, 12005.
(61) Gerfaud, T.; Chiang, Y.-L.; Kreituss, I.; Russak, J.; Bode, J. W.; external page"Enantioselective, chromatography-free synthesis ofβ3-amino acids with natural and unnatural side chains"call_made Org. Process Res. Dev. 2012, 16, 687–696.
(60) Fukuzumi, T.; Ju, L.; Bode, J. W. external page"Chemoselective Cyclization of Unprotected Linear Peptides by alpha-Ketoacid–Hydroxyamine Amide-Ligation"call_made Org. Biomol. Chem. 2012, 10, 5837–5844.
- This article is part of the collection: Organic & Biomolecular Chemistry 10th Anniversary.
(59) Book chapter: Chiang, P.-C.; Bode, J. W. "N-Heterocyclic Carbene Catalyzed Reactions of alpha-Functionalized Aldehydes", Science of Synthesis: Asymmetric Organocatalysis, Vol. 1, 2012, Georg Thieme Verlag, 639–672. [Ed: B. List]
(58) Mahatthananchai, J.; Kaeobamrung, J.; Bode, J. W. external page"Chiral N-Heterocyclic Carbene-Catalyzed Annulations of Enals and Ynals with Stable Enols: A Highly Enantioselective Coates–Claisen Rearrangementcall_made" ACS Catal. 2012, 2, 494–503.
- external pageSpecial issue on catalysis at ETH Zürichcall_made
(57) Pusterla, I.; Bode, J. W. external page"The Mechanism of the α-Ketoacid–Hydroxylamine (KAHA) Amide-Forming Ligation"call_made Angew. Chem. Int. Ed. 2012, 51, 513–516.
(56) Mahatthananchai, J.; Bode, J. W. external page"The effect of the N-mesityl group in NHC-catalyzed reactions"call_made Chem. Sci. 2012, 3, 192–197.
(55) Huang, Y.-L.; Frey, R; Juarez-Garcia, M. E.; Bode, J. W. external page"Synthesis of Aza-Surfactin and 3-Epi-aza-surfactin"call_made Heterocycles 2012, 84, 1179–1191
(54) Review article: Pattabiraman, V.; Bode, J. W. external page"Rethinking Amide Bond Synthesis”call_made Nature 2011, 480, 471–479.
(53) Binanzer, M.; Hsieh S.-Y.; Bode, J. W. external page"Catalytic Kinetic Resolution of Cyclic Secondary Amines"call_made J. Am. Chem. Soc. 2011, 133, 19698–19701.
- external pagereviewedcall_made in Synfacts 2012, 8, 211.
(52) Wanner, B.; Mahatthananchai, J.; Bode, J. W. external page"Enantioselective Synthesis of Dihydropyridinones via NHC-Catalyzed Aza-Claisen Reactioncall_made" Org. Lett. 2011, 13, 5378–5381.
(51) Schäfer, G.; Bode, J. W. external page"Friedel-Crafts Benzylation of Activated and Deactivated Arenes"call_made Angew. Chem. Int. Ed. 2011, 50, 10913–10916.
- external pagereviewedcall_made in Synfacts 2012, 8, 194.
- external pagehighlightedcall_made in Org. Process Res. Dev. 2012, 16, 526–534.
- external pagehighlightedcall_made in Organic Chemistry Portal.
(50) He, M.; Bode, J. W. external page"Racemization as a stereochemical measure of dynamics and robustness in shape-shifting organic molecules"call_made Proc. Nat. Acad. Sci. U.S.A. 2011, 36, 14752–14756.
(49) Wu, J.; J. Ruiz-Rodríguez; Comstock, J. M.; Dong, J. Z.; Bode, J. W. external page"Synthesis of human GLP-1 (7–36) by chemoselective α-ketoacid–hydroxylamine peptide ligation of unprotected fragments"call_made Chem. Sci. 2011, 2, 1976–1979.
(48) Vo, C.-V; Mitchell, T. A.; Bode, J. W. external page"Expanded Substrate Scope and Improved Reactivity of Ether-Forming Cross-Coupling Reactions of Organotrifluoroborates and Acetals"call_made J. Am. Chem. Soc. 2011, 133, 14082–14089.
- external pagehighlightedcall_made in Organic Chemistry Portal.
(47) Perspective: Bode, J. W. external page"Organic Synthesis without Stoichiometric Reagents: A Guiding Principle for Reaction Development"call_made Chimia 2011, 65, 150–156.
(46) Review article: Chiang, P.-C.; Bode, J. W. external page"N-Mesityl Substituted Chiral Triazolium Salts: Opening a New World of N-Heterocyclic Carbene Catalysis"call_made TCI MAIL 2011, 149, 2–17.
(45) Chiang, P.-C.; Bode, J. W. external page"On the Role of CO2 in NHC-Catalyzed Oxidation of Aldehydes"call_made Org. Lett. 2011, 13, 2422–2425.
(44) Mahatthananchai, J.; Zheng, P.; Bode, J. W. external page"α,β-Unsaturated Acyl Azoliums from N-Heterocyclic Carbene Catalyzed Reactions: Observation and Mechanistic Investigation"call_made Angew. Chem. Int. Ed. 2011, 50, 1673–1677.
(43) Zheng, P.; Gondo, C. A.; Bode, J. W. external page"Late-Stage Diversification of Chiral N-Heterocyclic-Carbene Precatalysts for Enantioselectvie Homoenolate Additions"call_made Chem. Asian J. 2011, 6, 614–620.
(42) Book chapter: Hackenberger, C. P. R.; Bode, J. W.; Schwarzer, D. external page"Chemoselective Peptide Ligation: A Privileged Tool for Protein Synthesis"call_made Amino Acids, Peptides and Proteins in Organic Chemistry: Building Blocks, Catalysis and Coupling Chemistry, Volume 3 (ed A. B. Hughes), 2011.
(41) Review article: Chiang, P.-C.; Bode, J. W. external page"N-Heterocyclic Carbenes as Organic Catalysts"call_made in N-Heterocyclic Carbenes: From Laboratory Curiosities to Efficient Synthetic Tools; Díez-González, S., Ed.; RSC Catalysis Series No. 6; Royal Society of Chemistry: Cambridge, 2011; pp 399–435. (DOI: 10.1039/9781849732161-00399)
(40) Lippert, A. R.; Naganawa, A.; Keleshian, V. L.; Bode, J. W. external page"Synthesis of Phototrappable Shape-Shifting Molecules for Adaptive Guest Binding"call_made J. Am. Chem. Soc. 2010, 132, 15790–15799.
(39) Narumi, T.; Bode, J. W. external page"α,α-Dicholoroisoxazolidinones for the Synthesis and Chemoselective Peptide Ligation of α-Peptide α-Ketoacids"call_made Heterocycles 2011, 82, 1515–1525.
(38) Kaeobamrung, J.; Kozlowski. M. C.; Bode, J. W. external page"Chiral N-Heterocyclic Carbene-Catalyzed Generation of Ester Enolate Equivalents from α,β-Unsaturated Aldehydes for Enantioselective Diels–Alder Reactions"call_made Proc. Nat. Acad. Sci. U.S.A. 2010, 107, 20661–20665.
(37) Yu, S.; Ishida, H.; Juarez-Garcia, M. E.; Bode, J. W. external page"Unified synthesis of enantiopure β2h, β3h and β2,3-amino acids"call_made Chem. Sci. 2010, 637–641.
(36) Kaeobamrung, J.; Mahatthananchai, J.; Zheng, P.; Bode, J. W. external page"An Enantioselective Claisen Rearrangement Catalyzed by N-Heterocyclic Carbenes"call_made J. Am. Chem. Soc. 2010, 132, 8810–8812.
- external pagereviewedcall_made in Synfacts 2010, issue 09, 1071.
(35) Struble, J. R.; Bode, J. W. external page"Synthesis of N-Mesityl Substituted Aminoindalnol-Derived Triazolium Salt [(5aS,10bR)-5a,10b-Dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b]-1,2,4-triazolo[4,3-d]-1,4-oxazinium chloride]"call_made Org. Synth. 2010, 87, 362–376.
(34) Ju, L.; Bode, J. W. external page"Amide Formation by Decarboxylative Condensation of Hydroxyamines and α-Ketoacids: N-[(1S)-1-Phenylethyl]-benzeneacetamide"call_made Org. Synth. 2010, 87, 218–225.
(33) Juarez-Garcia, M. E.; Yu, S.; Bode, J. W. external page"Asymmetric Synthesis of Enantiopure Isoxazolidinone Monomers for the Synthesis of β3-Oligopeptides by Chemoselective Amide Ligation"call_made Tetrahedron 2010, 66, 4841–4853.
(32) Medina, S. I.; Wu, J.; Bode, J. W. external page"Nitrone Protecting Groups for Enantiopure N-Hydroxyamino Acids: Synthesis of N-Terminal Peptide Hydroxylamines for Chemoselective Ligations"call_made Org. Biomol. Chem. 2010, 8, 3405–3417.
(31) Flores, M. A.; Bode, J. W. external page"Chemoselective Protection of α-Ketoacids by Direct Annulations with Oximes"call_made Org. Lett. 2010, 12, 1924–1927.
(30) Mitchell, T. A.; Bode, J. W. external page"Synthesis of Dialkyl Ethers from Organotrifluoroborates and Acetal"call_made J. Am. Chem. Soc. 2009, 131,18057–18059.
- external pagereviewedcall_made in Synfacts 2010, issue 03, 335.
(29) Chiang, P.-C.; Kim, Y.; Bode, J. W. external page"Catalytic Amide Formation with α'-Hydroxyenones as Acylating Reagents"call_made Chem. Commun., 2009, 4566–4568.
- external pagereviewedcall_made in Synfacts 2009, issue 09, 1042.
(28) Chiang, P.-C.; Rommel, M.; Bode, J. W. external page"α'-Hydroxyenones as Mechanistic Probes and Scope-Expanding Surrogates for α,β-Unsaturated Aldehydes in N-Heterocyclic Carbene-Catalyzed Reactions"call_made J. Am. Chem. Soc. 2009, 131, 8714–8718.
(27) Valenta, P.; Drucker, N. A.; Bode, J. W. and Walsh, P. J. external page"Simple One-pot Conversion of Aldehydes and Ketones to Enals"call_made Org. Lett. 2009, 11, 2117–2119.
(26) Fukuzumi, T.; Bode, J. W. external page"A Reagent for the Convenient, Solid-Phase Synthesis of N-Terminal Peptide Hydroxylamines for Chemoselective Ligations"call_made J. Am. Chem. Soc. 2009, 131, 3864–3865.
(25) Struble, J. R.; Bode, J. W. external page"Formal Synthesis of Salinosporamide A via NHC-catalyzed Intramolecular Lactonization"call_made Tetrahedron, 2009, 65, 4957–4967.
(24) Ishida, H.; Carrillo, N.; Bode, J. W. "external pageSynthesis of an enantiopure isoxazolidine monomer for β3-aspartic acid in chemoselective β-oligopeptide synthesis"call_made Tetrahedron Lett. 2009, 50, 3258–3260.
(23) Ju, L.; Bode, J. W. external page"A general strategy for the preparation of C-terminal peptide a-ketoacids by solid phase peptide synthesis"call_made Org. Biomol. Chem. 2009, 7, 2259–2264.
(22) Lippert, A. R.; Keleshian, V. L.; Bode, J. W. external page"Dynamic supramolecular complexation by shapeshifting organic molecules"call_made Org. Biomol. Chem. 2009, 7, 1529–1532.
(21) Kaeobamrung, J.; Bode, J. W. external page"Stereodivergency of Triazolium and Imidazolium-Derived NHCs for Catalytic, Enantioselective Cyclopentane Synthesis"call_made Org. Lett. 2009, 11, 677–680.
(20) Rommel, M.; Fukuzumi, T.; Bode, J. W. external page"Cyclic Ketimines as Superior Electrophiles for NHC-Catalyzed Homoenolate Additions with Broad Scope and Low Catalyst Loadings"call_made J. Am. Chem. Soc. 2008, 130, 17266–17267.
- external pagereviewedcall_made in Synfacts 2009, issue 02, 216.
(19) He, M.; Beahm, B. J.; Bode, J. W. external page"Chiral NHC-Catalyzed Oxodiene Diels−Alder Reactions with alpha-Chloroaldehyde Bisulfite Salts"call_made Org. Lett. 2008, 10, 3817–3820.
(18) Struble, J. R.; Bode, J. W. external page"A modular synthesis of chiral aminoindanol-derived imidazolium salts"call_made Tetrahedron 2008, 64, 6961–6972.
(17) Ju, L.; Lippert, A. R.; Bode, J. W. external page"Stereoretentive Synthesis and Chemoselective Amide-Forming Ligations of C-Terminal Peptide alpha-Ketoacids"call_made J. Am. Chem. Soc. 2008, 130, 4253–4255.
(16) Struble, J.R.; Kaeobamrung, J.; Bode, J.W. external page"Synthesis of an N-Mesityl Substituted Chiral Imidazolium Salt for NHC-Catalyzed Reactions"call_made Org. Lett. 2008, 10, 957–960.
- external pagereviewedcall_made in Synfacts 2008, issue 06, 645.
(15) He, M.; Bode, J. W. external page"Enantioselective, NHC-Catalyzed Bicyclo-beta-Lactam Formation via Direct Annulations of Enals and Unsaturated N-Sulfonyl Ketimines"call_made J. Am. Chem. Soc. 2008, 130, 418–419.
- external pagereviewedcall_made in Synfacts 2008, issue 03, 307.
(14) Bode, J. W.; Sohn, S. S. external page"N-Heterocyclic Carbene-Catalyzed Redox Amidations of alpha-Functionalized Aldehydes with Amines"call_made J. Am. Chem. Soc. 2007, 129, 13798–13799.
(13) Chiang, P.-C.; Kaeobamrung, J.; Bode, J. W. external page"Enantioselective, Cyclopentene-Forming Annulations via NHC-Catalyzed Benzoin–Oxy-Cope Reactions"call_made J. Am. Chem. Soc. 2007, 129, 3520–3521.
- external pagereviewedcall_made in Synfacts 2007, issue 05, 545.
(12) He, M.; Uc, G. J.; Bode, J. W. external page"Chiral, N-Heterocyclic Carbene Catalyzed Oxodiene Diels-Alder Reactions with Low Catalyst Loadings"call_made J. Am. Chem. Soc. 2006, 128, 15088–15089.
- external pagereviewedcall_made in Synfacts 2007, issue 01, 100.
(11) Review article: Bode, J. W. external page"Emerging Methods for the Synthesis of Amide and Peptide Bonds"call_made Curr. Opin. Drug Discov. Devel. 2006, 9, 765–775.
(10) Lippert, A. R.; Kaeobamrung, J.; Bode, J. W. external page"Synthesis of Oligosubstituted Bullvalones: Shapeshifiting Molecules Under Basic Conditions "call_made, J. Am. Chem. Soc. 2006, 128, 14738–14739.
(9) Sohn, S. S.; Bode, J. W. external page"N-Heterocyclic Carbene Catalyzed C–C Bond Cleavage in Redox Esterifications of Chiral Formylcyclopropanes"call_made Angew. Chem. Int. Ed. 2006, 6021–6024.
- external pagereviewedcall_made in Synfacts 2006, issue 10, 1060.
(8) He, M.; Struble, J. R.; Bode, J. W. external page"Highly Enantioselective Azadiene Diels-Alder Reactions Catalyzed by Chiral N-Heterocyclic Carbenes"call_made J. Am. Chem. Soc. 2006, 128, 8418–8420.
- external pagereviewedcall_made in Synfacts 2006, issue 08, 840.
(7) Carrillo, N.; Davalos, E. A.; Russak, J. A.; Bode, J. W. external page"Iterative, Aqueous Synthesis of b3-oligopeptides without Coupling Reagents"call_made J. Am. Chem. Soc. 2006, 128, 1452-1453.external pagecall_made
- external pagehighlightedcall_made in C&E News.
(6) Bode, J. W.; Fox, R. M.; Baucom, K. D. external page"Decarboxylative Condensations of alpha-Ketoacids and N-Alkylhydroxylamines: A New Amide Ligation Reaction"call_made Angew. Chem. Int. Ed. 2006, 45, 1248-1252.
- external pagehighlightedcall_made in C&E News.
(5) Sohn, S.; Bode, J. W. external page"Catalytic Generation of Activated Carboxylates from Enals: A Product Determining Role for the Basecall_made" Org. Lett. 2005, 7, 3873-3876.external pagecall_made
- external pagecategorizedcall_made in Organic Chemistry Portal.
(4) He, M.; Bode, J. W. external page"Catalytic Synthesis of gamma-Lactams via Direct Annulations of Enals and N-Sulfonylimines"call_made Org. Lett. 2005, 7, 3131–3134.
- external pagehighlightedcall_made in Angew. Chem. Int. Ed. 2005, 44, 7506.
(3) Bode, J. W. external page"Reactor, Chem Axon"call_made J. Am. Chem. Soc. 2004, 126, 15317. (Software Review)
(2) Sohn, S. S.; Rosen, E. L.; Bode, J. W. external page"N-Heterocyclic Carbene-Catalyzed Generation of Homoenolates: gamma-Butyrolactones by Direct Annulations of Enals and Aldehydes"call_made J. Am. Chem. Soc. 2004, 126, 14370-14371.
- external pagehighlightedcall_made in Angew. Chem. Int. Ed. 2005, 44, 7506.
(1) Chow, K. Y.-K.; Bode, J. W. external page"Catalytic Generation of Activated Carboxylates: Direct, Stereoselective Synthesis of beta-Hydroxyesters from Epoxyaldehydes"call_made J. Am. Chem. Soc. 2004, 126, 8126–8127.
- external pagehighlightedcall_made in Angew. Chem. Int. Ed. 2005, 44, 7506.
- Suzuki, K.; Takikawa, H.; Hachisu, Y.; Bode, J. W. external page"Isoxazole-directed pinacol rearrangement: stereocontrolled approach to angular stereogenic centers"call_made Angew. Chem. Int. Ed. 2007, 46, 3252–3254.
- Takikawa, H.; Hachisu, Y.; Bode, J. W.; Suzuki, K. external page"Catalytic, Enantioselective Crossed Aldehyde–Ketone Benzoin Cyclizations”call_made Angew. Chem. Int. Ed. 2006, 45, 3492–3494.
- Hachisu, Y.; Bode, J. W.; Suzuki, K. external page"Thiazolium Ylide Catalyzed Intramolecular Aldehyde--Ketone Benzoin-Forming Reactions: Substrate Scope"call_made Adv. Syn. Cat. 2004, 1097–1100.
- Matsuura, T.; Bode, J. W.; Hachisu, Y.; Suzuki, K. external page"Molecular Sieve (MS 4A) Promoted Cyclocondensation of Hindered, Aromatic Nitrile Oxides and Cyclic Diketones under Mild Conditions"call_made Synlett 2003, 1746-1748.
- Hachisu, Y.; Bode, J. W.; Suzuki, K. external page"Catalytic Intramolecular Aldehyde-Ketone Benzoin Reactions: A Novel Synthesis of Functionalized Preanthraquinones"call_made J. Am. Chem. Soc. 2003, 125, 8432-8433.
- Bode, J. W.; Hachisu, Y.; Matsuura, T.; Suzuki, K. external page"Amine-Promoted Cyclocondensation of Highly Substituted Aromatic Nitrile Oxides with Diketones"call_made Tetrahedron Lett. 2003, 44, 3555-3558.
- Bode, J. W.; Suzuki K. external page"Structural Incongruities of Coleophomone Natural Products: Insights by Total Synthesis of a Semi-Synthetic Derivative"call_made Tetrahedron Lett. 2003, 44, 3559-3563.
- Bode, J. W.; Hachisu, Y.; Matsuura, T.; Suzuki, K. external page"Facile Construction and Divergent Transformation of Polycyclic Isoxazoles: Direct Access to Polyketide Architectures"call_made Org. Lett. 2003, 5, 391-394.
- Bode, J. W.; Uekusa, H.; Suzuki, K. external page"Rearrangement Promoted Cascade Reactions for the Stereoselective Synthesis of Highly Functionalized Polycycles"call_made Org. Lett. 2003, 5, 395-398.
- Bode, J. W.; Gauthier, D. R.; Carreira, E. M. external page"Facile Enantioselective Synthesis of a Key Homoallylic Alcohol Building Block for Polyketide Synthesis: TiF4-BINOL Catalyzed Allylsilylation"call_made J. Chem. Soc. Chem. Comm. 2001, 2560-2561.
- Bode, J. W.; Carreira, E. M. external page"Stereoselective Syntheses of Epothilones A and B via Nitrile Oxide Cycloadditions and Related Studies"call_made J. Org. Chem. 2001, 66, 6410-6424.
- Bode, J. W.; Carreira, E. M. external page"A Mild and Chemoselective Method for the Reduction of Conjugated Isoxazolines to Beta-Hydroxy Ketones"call_made Org. Lett. 2001, 3, 1587-1590.
- Bode, J. W.; Fraefel, N.; Muri, D.; Carreira, E. M. external page"A General Solution to the Modular Synthesis of Polyketide Building Blocks via Kanemasa Hydroxyl-Directed Nitrile Oxide Cycloadditions"call_made Angew. Chem. Int. Ed. 2001, 40, 2082-2085.
- Bode, J. W.; Carreira, E. M. external page"Stereoselective Syntheses of Epothilones A and B via Hydroxyl Directed Nitrile Oxide Cycloadditions"call_made J. Am. Chem. Soc. 2001, 123, 3611-3612.
- Muri, D.; Bode, J. W.; Carreira, E.M. external page"A Novel, General Method for the Synthesis of Nitrile Oxides: Dehydration of O-Silylated Hydroxamic Acids"call_made Org. Lett. 2000, 2, 539-541.
- Bode, J. W.; Carreira, E. M. external page"Total Synthesis of Macrolides"call_made in The Chemical Synthesis of Natural Products; Hale, K. J., Ed.; Sheffield Academic Press: Sheffield, 2000; pp 40-63.
- Bode, J. W.; Doyle, M. P.; Protopopova, M. N. Zhou, Q-L. external page"Intramolecular Regioselective Insertion into Unactivated Carbon-Hydrogen Bonds with Diazoacetates of Primary Alcohols Catalyzed by Chiral Dirhodium(II) Carboxamidates. Highly Enantioselective Total Synthesis of Natural Lignan Lactones"call_made J. Org. Chem. 1996, 61, 9146-9155.
- Doyle, M.P.; Protopopova, M.N. Zhou, Q.-L.; Bode, J. W.; Simonsen, S.H.; Lynch, V. external page"Optimization of Enantiocontrol for Carbon-Hydrogen Insertion with Chiral Dirhodium(II) Carboxamidates. Synthesis of Natural Dibenzylbutyrolactone Lignans from 3-Aryl-1-Propyl Diazoacetates in High Optical Purity"call_made J. Org. Chem. 1995, 60, 6654-6655.