Open Source Notes
Past OC VI Lecture Notes
|Topics||Note Files||Update Year|
|Asymmetric Hydrogenation||PDF (PDF, 1.6 MB) | Word (DOC, 5.6 MB)||2015|
|Catalyst Design, Synthesis and Screening||PDF (PDF, 4.6 MB) | Word (DOCX, 9.1 MB)||2012|
|Catalytic C-H Functionalization||PDF (PDF, 1.4 MB) | Word (DOCX, 2.9 MB)||2012|
|Catalytic Divergent Synthesis||PDF (PDF, 2.1 MB) | Word (DOC, 4.6 MB)||2011|
|Catalytic Enantioselective 1,2 Additions||PDF (PDF, 2.1 MB) | Word (DOCX, 4.9 MB)||2012|
|Catalytic Enantioselective 1,4 Additions||PDF (PDF, 1.8 MB) | Word (DOC, 8.2 MB)||2015|
|Catalytic Enantioselective Synthesis of Amino Acids||PDF (PDF, 1.3 MB) | Word (DOC, 2.8 MB)||2015|
|Cooperative Catalysis||PDF (PDF, 2.1 MB) | Word (DOCX, 3.3 MB)||2015|
|Enantioselective Aldol Reactions||PDF (PDF, 1.6 MB) | Word (DOCX, 3.7 MB)||2011|
|Enantioselective Olefin Addition Reactions||PDF (PDF, 2.4 MB) | Word (DOC, 3.6 MB)||2015|
|Fluorination||PDF (PDF, 1.5 MB) | Word (DOCX, 3.5 MB)||2012|
|Key Concepts in Catalysis, Thermodynamics and Kinetics||PDF (PDF, 3.6 MB) | Word (DOC, 11.8 MB)||2015|
|Key Concepts in Stereoselective Synthesis||PDF (PDF, 1.7 MB) | Word (DOC, 3 MB)||2015|
|Kinetic Resolution and Desymmetrization||PDF (PDF, 4.4 MB) | Word (DOCX, 4.5 MB)||2015|
|Ligation and Bioconjugation||PDF (PDF, 1.7 MB) | Word (DOCX, 5.5 MB)||2015|
|Machine-Assisted Organic Synthesis||PDF (PDF, 1.9 MB) | Word (DOCX, 3.4 MB)||2015|
|N-Heterocyclic Carbene Catalysis||PDF (PDF, 3.7 MB) | Word (DOC, 7.5 MB)||2013|
|Photoredox Catalysis||PDF (PDF, 1.6 MB) | Word (DOCX, 2.9 MB)||2015|
|Saturated N-Heterocycle Synthesis||PDF (PDF, 1.7 MB) | Word (DOCX, 3.3 MB)||2015|
|Selective Catalysis||PDF (PDF, 2.6 MB) | Word (DOCX, 4.7 MB)||2015|
About these notes
These chapters were written and illustrated by the PhD students and postdocs in Professor Bode’s research group at ETH-Zürich as the “script” for OC VI: Advanced Methods and Strategies in Organic Chemistry. Professor Bode’s group members (and a few from the Hilvert group) put an enormous amount of time and effort into preparing these chapters! They are designed to present the background and development of both historical and contemporary topics in organic chemistry. All entries are based on the primary literature and citations provided. In nearly all cases, the schemes have been redrawn in Chemdraw and are available for use or modification without copyright violations. The notes are updated from time to time and 2-3 new chapters per year are created. In a future project, we will prepare these notes in eBook format for better reading on tablet devices.
How can I use these notes?
These notes can be used as a reference or study guide. We are making available the original word files with editable Chemdraw. Please use Chemdraw 12.0.3 and Word 2011 14.4.3 (for Macintosh) to ensure that the Chemdraw structures are available for “round-trip editing”. You may use all or part of the notes for your own projects, classes, or chapters provided the following conditions are met.
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If you choose to reuse or repost these materials you must give proper attribution to the original author(s). Please utilize the following citation:
[Name], [Course Title], [Topic], [Semester]. (ETH-Zürich), [URL] (Accessed [Date]). License: Creative commons BY-NC-SA
Jeffrey W. Bode, OC IV: Advanced Methods and Strategies in Synthesis, Key Concepts in Stereoselective Synthesis, 2013. (ETH-Zürich), http://www.bode.ethz.ch/lecturenote. License: Creative commons BY-NC-SA
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What if I find mistakes?
There are mistakes in these chapters. If you find one, please let us know or –better yet – fix the mistake and send us the revised Word file. We cannot cite every paper on every topic and there are certainly omissions. If we are missing key references or precedents please incorporate them into the documents and send us the new files. We’ll do our best to correct everything in the new editions, which we usually update once a year.