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AS-48 get!
Congratulations to Florian Rohrbacher and André Zwicky on their new publication in Chemical Science! This paper details the successful chemical synthesis of a antibacterial variant of the cyclic protein AS-48 - a formidably challenging target for any peptide chemist. Biological studies were also carried out on the protein, providing further evidence of its suspected mechanism of action. Great work, guys!
Congratulations Dr. Murar!
Massive congratulations to peptide queen Claudia Murar, who successfully defended her PhD thesis today! Claudia's work on the development of the KAHA ligation and its application in protein chemical synthesis has led to a slew of publications and patents, as well as directly inspiring many ongoing projects in the group. Claudia's presence will be treasured here for a little longer as she explores the entrepreneurial possibilities of her PhD work. But first things first: it's champagne time!
Congratulations Dr. Lüscher!
Huge congratulations to SnAP supremo Dr. Michael Lüscher, who yesterday became our first PhD graduate of 2017! Michael joined the Bode group when SnAP chemistry was in its infancy, and soon became a pivotal figure in its rapid development into the versatile and powerful methodology we know today, with 14 commercially available reagents and four papers on the topic to his name. Michael will soon depart for post-doctoral life at Harvard, and we wish him all the best with everything to come.